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Скачать Science, August 8, 2008 бесплатно

Science, August 8, 2008
PDF | English | 120 pages | 10.1 MB

Simulation of a vesicle interacting with a lipid bilayer (lipid head groups in green and blue, tails in cyan; water is not shown). The computation uses a coarse-grained model with over 1 million interaction sites, equivalent to more than 10 million atoms.

Special Section: Challenges in Theoretical Chemistry
Not so long ago, Experiments in the synthetic chemistry lab tended to proceed without detailed calculations and predictions. Today, most organic chemists rely on the results of density functional theory (DFT) calculations to help decide between alternative synthetic routes and to provide guidance on structure assignments. However, such readily solved problems are not where theoretical chemists focus their attention for their own current day-to-day work -- rather, it is on the problems that still defy solution. This special section highlights some areas where theorists feel that progress can be made in the near future on problems that will benefit their experimental colleagues in chemistry and other disciplines.

Deciphering the Genetics of Evolution
Powerful personalities in evolutionary biology have been tussling over how the genome changes to set the stage for evolution.

Industrial-Style Screening Meets Academic Biology
A $100-million-a-year-effort to find chemicals for exploring cellular processes and drug discovery is about to move into production; skeptics say it is struggling to meet its goals.

Can the Vaquita Be Saved?
Scientists are embarking on a last-ditch effort to help the world's most endangered marine mammal avoid the fate of its Chinese cousin, the baiji.

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